JMIR Research Protocols

Most individuals vulnerable to depression do not receive adequate or timely treatment globally. Unguided computerized cognitive behavioral therapy (cCBT) has the potential to bridge this treatment gap. However, the real-world effectiveness of unguided cCBT interventions, particularly in low- and middle-income countries (LMICs), remains inconclusive. In this study, we report the design and development of a new unguided cCBT intervention, TreadWill, and its pragmatic evaluation. TreadWill was desi...

PurposeProlonged Grief Disorder (PGD), recently included in the DSM-5-TR and ICD-11, involves a strong yearning for the deceased, fixation on death, denial, avoidance, negative emotions, and disengagement from daily life, lasting at least six months. However, most studies focus on Western settings, leading to underdiagnosis, inadequate care, and a growing mental health burden in Viet Nam. DesignExperience sampling method (ESM) can provide detailed, real-time data on daily symptoms due to the wa...

IntroductionAutism is a neurodevelopmental disorder that can cause repetitive behavior, limited activity, and a lack of ability to communicate and socialize. The purpose of this literature review is to identify the effectiveness of Complementary mind-body-spirit therapies, manipulative and body-based therapies, and energy therapies in children with autism. MethodLiterature search method using ProQuest, PubMed, and Science Direct databases with include the keywords Complementary therapy in child...

BackgroundAdverse events are serious and frequent complications most often linked to the quality of nursing care. PurposeWe evaluated the compliance to traceability of nursing care at bedside using the Patient Smart Reader(R), a personal digital assistant with a barcode. MethodsWe compared paper record forms, specific computer software in the hospital information system and the Patient Smart Reader(R). ResultsThe Patient Smart Reader enhanced the recording of 90% of nursing care surveyed. Reg...

BackgroundAdolescent pregnancy constitutes a critical public health issue worldwide. Young mothers face substantial physical and psychological changes as they transition to motherhood, while limited knowledge, experience, and maturity may impair parenting and increase stress. The aim of the study was to evaluate the effects of the parental enhancing program with mobile application on parental stress and competence among adolescent postpartum women. MethodsA quasi-experimental study was conducte...

BackgroundAutism Spectrum Disorder (ASD) is a neurodevelopmental condition requiring early identification and intervention to improve outcomes. Nurses are key to ASD care, facilitating referrals and supporting interventions, but often face knowledge gaps and limited training. In Kazakhstan, rising diagnoses of ASD, and healthcare reforms highlight the need for nurse education, yet challenges remain underexplored. This study examines nurses knowledge, beliefs, challenges in practice, training bar...

One component of a systematic review is the quality assessment of studies to determine their inclusion or exclusion. Studies on e-cigarettes are conducted in the contentious atmosphere surrounding tobacco harm reduction, which has resulted at times in research bias. Therefore, the quality assessment of studies on e-cigarettes requires more scrutiny than what is provided by generic tools on study design. This topic-specific quality assessment must examine the tests, measurements, and analysis met...

Background: Nursing interns are at high risk of psychological distress due to academic and clinical stressors. While poor sleep quality is linked to anxiety and depression, the buffering role of social support remains underexplored in this population. Aims: To explore the role of social support in regulating the relationship between sleep and mental health among nursing interns. Methods: A total of 396 nursing interns completed self-administered questionnaires including the Pittsburgh Sleep Qual...

BackgroundDepression is a leading global cause of disability, significantly affecting individuals quality of life and contributing to a substantial worldwide health burden. Self-help practices have emerged as cost-effective and scalable strategies for managing mild to moderate depression, empowering individuals to take an active role in their mental health care. Theory-based interventions, which are grounded in established psychological frameworks, provide a systematic approach to designing, imp...

BackgroundDevelopmental Coordination Disorder (DCD) is a common neurodevelopmental disorder. Children with DCD usually need treatment. Indications for intervention are essentially dependent on the influence of the diagnosis on activities of daily life and the proposed treatments are therefore heterogeneous. ObjectivesIdentifying and describing the current state of knowledge regarding the treatments available in the literature for the treatment of DCD, defining which of these interventions have ...

Nursing admission assessment is a critical first step in the inpatient care process, providing essential information for clinical decision-making and patient safety. However, despite its importance, this process places a significant burden on nurses, who face challenges such as time pressure, documentation overload, and communication barriers, particularly among elderly patients. This qualitative descriptive study explores the experiences of nurses, patients, and caregivers regarding the nursing...

BackgroundAging is a social concern. Despite increased incidence of depression in Chinese older populations, they are often misdiagnosed and undertreated, which pose a challenge to our health care system. Depressed older adults often suffer from lack of motivation. Evidence-based guided self-help behavioral activation treatment is effective in reducing anhedonia and amotivation symptoms, however the efficacy in in elderly depressed patients are unknown yet. So the current study aim to pilot the ...

Subthreshold depression is a substantial risk factor for the development of major depression. It is associated with poorer health, functional disabilities, and reduced quality of life in older adults. There is a paucity of cost-effective psychosocial interventions for this population in primary care worldwide, particularly in low- and middle-income countries. We present a protocol for evaluating the effectiveness and cost-effectiveness of the Viva Vida programme, a 6-week self-help digital psych...

ObjectiveThis clinical trial sought to evaluate the safety and preliminary efficacy of psilocybin and MBSR for frontline healthcare providers with symptoms of depression and burnout related to the COVID-19 pandemic. MethodsThis was a randomized controlled trial that enrolled physicians and nurses with frontline clinical work during the COVID-19 pandemic and symptoms of depression and burnout. Participants were randomized in a 1:1 ratio to either an 8-week MBSR curriculum alone or an 8-week MBSR...

BackgroundBehavioral activation (BA) is a psychotherapy that directly approaches patients most valued daily activities. BA may be particularly useful for treating depression in patients with cancer, but there is insufficient evidence in this population. This study aimed to verify the feasibility and preliminary effectiveness of BA for patients with depression with all types and stages of cancer. MethodsThis pre-post study without a control group was conducted in patients with cancer and depress...

This prospective observational study reports on the feasibility and adequacy of feasibility and adequacy of Level 2 polysomnography involving children with autism spectrum disorder during an interventional-randomised controlled trial. Multiple level 2 polysomnographic studies were performed using Nox-A1 devices worn between October 2023 and September 2024. Study feasibility was determined by the childs compliance and primary caregiver report, while signal quality (key channels present for at le...

IntroductionSelective Mutism (SM) is an anxiety disorder affecting some children starting school. Usual presentation is lack of speech at school, contrasting with confident speech at home. Estimated prevalence is 0.7%, rising to 2.2% for children who are second language learners. Long-term impacts include complex mental health conditions for children not receiving timely intervention. There are calls for effective treatments as part of a multi-modal care pathway. Case study research describes mu...

Background and aimsChildren with neurodevelopmental disorders (NDDs) such as Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) may exhibit medical and neurocognitive comorbidities requiring periodic medical check-ups. In addition, children with NDDs often experience language difficulties that hamper an effective communication in the healthcare setting, with potential deleterious effects on their compliance. In turn, these challenges may affect accessing healthcare resources and rec...

BackgroundApproximately 13.4% of children and adolescents worldwide suffer from depression, with early onset often manifesting before the age of 14 and disproportionately affecting vulnerable groups. The prevalence of adolescent depression has increased since the COVID-19 pandemic, with significant long-term impacts on development, social functioning, and academic performance. Mentalization-based treatment (MBT), particularly the MBT-A model tailored for adolescents, has shown promise in address...

PurposeTo describe children with 22q11.2 deletion syndrome functioning from a biopsychosocial perspective, focusing on the impact of childrens health condition from domains to the International Classification of Functioning, Disability and Health (ICF). MethodsA descriptive, cross-sectional case series study with 22q11.2del children. A questionnaire with an ICF checklist for 22q11.2del was completed using a structured interview. The Test of Childhood Language ABFW was used to fill in vocabulary...